Ki Summary

Reaction Details

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Target

Major surface glycoprotein G

Ligand

BDBM194739

Substrate/Competitor

n/a

Meas. Tech.

Viral Cytopathic Effect (CPE) Assay

Citation

Gao, L; Guo, L; Liang, C; Wang, B; Wang, L; Yun, H; Zhang, W; Zheng, X Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection US Patent US9670211 Publication Date 6/6/2017

More Info.:

Get all data from this article, Assay Method

Major surface glycoprotein G

Name:

Major surface glycoprotein G

Synonyms:

Attachment glycoprotein G | G | GLYC_HRSV | Membrane-bound glycoprotein | mG

Type:

Protein

Mol. Mass.:

32805.15

Organism:

Human respiratory syncytial virus A (strain Long)

Description:

P20895

Residue:

298

Sequence:

MSKNKDQRTAKTLEKTWDTLNHLLFISSGLYKLNLKSIAQITLSILAMIISTSLIITAII
FIASANHKVTLTTAIIQDATSQIKNTTPTYLTQDPQLGISFSNLSEITSQTTTILASTTP
GVKSNLQPTTVKTKNTTTTQTQPSKPTTKQRQNKPPNKPNNDFHFEVFNFVPCSICSNNP
TCWAICKRIPNKKPGKKTTTKPTKKPTFKTTKKDLKPQTTKPKEVPTTKPTEEPTINTTK
TNITTTLLTNNTTGNPKLTSQMETFHSTSSEGNLSPSQVSTTSEHPSQPSSPPNTTRQ

BDBM194739

n/a

Name

BDBM194739

Synonyms:

US9670211, 2-7

Type

Small organic molecule

Emp. Form.

C23H23ClN4O2

Mol. Mass.

422.907

SMILES

OC1CCC(CC1)n1c(CN2C(=O)C3(CC3)c3ccncc23)nc2cc(Cl)ccc12 |(.94,6.53,;.54,5.04,;1.63,3.95,;1.23,2.46,;-.25,2.07,;-1.34,3.16,;-.94,4.64,;-.65,.58,;.25,-.67,;1.79,-.67,;2.56,-2,;4.1,-2,;4.87,-.67,;4.58,-3.47,;5.35,-4.8,;6.12,-3.47,;3.33,-4.37,;3.17,-5.9,;1.76,-6.53,;.52,-5.62,;.68,-4.09,;2.09,-3.47,;-.65,-1.91,;-2.12,-1.44,;-3.45,-2.21,;-4.78,-1.44,;-6.12,-2.21,;-4.78,.1,;-3.45,.87,;-2.12,.1,)|

Structure