Ki Summary

Reaction Details

Report a problem with these data

Target

Major surface glycoprotein G

Ligand

BDBM195068

Substrate/Competitor

n/a

Meas. Tech.

Viral Cytopathic Effect (CPE) Assay

Citation

Gao, L; Guo, L; Liang, C; Wang, B; Wang, L; Yun, H; Zhang, W; Zheng, X Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection US Patent US9670211 Publication Date 6/6/2017

More Info.:

Get all data from this article, Assay Method

Major surface glycoprotein G

Name:

Major surface glycoprotein G

Synonyms:

Attachment glycoprotein G | G | GLYC_HRSV | Membrane-bound glycoprotein | mG

Type:

Protein

Mol. Mass.:

32805.15

Organism:

Human respiratory syncytial virus A (strain Long)

Description:

P20895

Residue:

298

Sequence:

MSKNKDQRTAKTLEKTWDTLNHLLFISSGLYKLNLKSIAQITLSILAMIISTSLIITAII
FIASANHKVTLTTAIIQDATSQIKNTTPTYLTQDPQLGISFSNLSEITSQTTTILASTTP
GVKSNLQPTTVKTKNTTTTQTQPSKPTTKQRQNKPPNKPNNDFHFEVFNFVPCSICSNNP
TCWAICKRIPNKKPGKKTTTKPTKKPTFKTTKKDLKPQTTKPKEVPTTKPTEEPTINTTK
TNITTTLLTNNTTGNPKLTSQMETFHSTSSEGNLSPSQVSTTSEHPSQPSSPPNTTRQ

BDBM195068

n/a

Name

BDBM195068

Synonyms:

US9670211, 14-1

Type

Small organic molecule

Emp. Form.

C21H19ClN4O2

Mol. Mass.

394.854

SMILES

O[C@H]1C[C@H](C1)n1c(CN2C(=O)C3(CC3)c3ccncc23)nc2cc(Cl)ccc12 |r,wU:3.5,1.0,(.71,6.09,;.31,4.61,;1.08,3.27,;-.25,2.5,;-1.02,3.84,;-.65,1.01,;.25,-.23,;1.79,-.23,;2.56,-1.57,;4.1,-1.57,;4.87,-.23,;4.58,-3.03,;5.35,-4.36,;6.12,-3.03,;3.33,-3.94,;3.17,-5.47,;1.76,-6.09,;.52,-5.19,;.68,-3.66,;2.09,-3.03,;-.65,-1.48,;-2.12,-1,;-3.45,-1.77,;-4.78,-1,;-6.12,-1.77,;-4.78,.54,;-3.45,1.31,;-2.12,.54,)|

Structure