| Reaction Details |
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 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
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| Ligand | BDBM330189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay on Mouse |
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| IC50 | 881±n/a nM |
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| Citation |  Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 5-oxa-2-azabicyclo[2.2.2]OCTAN-4-yl and 5-oxa-2-azabicyclo[2.2.1]heptan-4-yl derivatives US Patent US9663530 Publication Date 5/30/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Trace amine-associated receptor 1 |
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| Name: | Trace amine-associated receptor 1 |
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| Synonyms: | TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 38034.73 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q923Y9 |
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| Residue: | 332 |
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| Sequence: | MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
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| BDBM330189 |
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| n/a |
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| Name | BDBM330189 |
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| Synonyms: | N-[4-[[(1S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]-5-(trifluoromethyl)pyrimidin-2-amine | US9663530, Example 33 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17F3N4O |
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| Mol. Mass. | 350.3383 |
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| SMILES | FC(F)(F)c1cnc(Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)nc1 |r| |
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| Structure | 
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