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TargetProkineticin receptor 1
LigandBDBM347561
Substrate/Competitorn/a
Meas. Tech.Biological Assay
IC50 460±n/a nM
Citation Bousba, SGoldby, AJenkins, KKinsella, NTeall, M Piperidine and azepine derivatives as prokineticin receptor modulators US Patent US9790201 Publication Date 10/17/2017
More Info.:Get all data from this article,  Assay Method
 
Prokineticin receptor 1
Name:Prokineticin receptor 1
Synonyms:G-protein coupled receptor 73 | G-protein coupled receptor ZAQ | GPR73 | GPR73a | PK-R1 | PKR1 | PKR1_HUMAN | PROKR1
Type:enzyme
Mol. Mass.:44779.92
Organism:Homo sapiens (Human)
Description:Q8TCW9
Residue:393
Sequence:
METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
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  Blast E-value cutoff:
BDBM347561
n/a
NameBDBM347561
Synonyms:4-{[3-(4-Methoxyphenyl)piperidin-1-yl]carbonyl}-N,N-dimethylpyridin-2-amine | US9790201, 47
TypeSmall organic molecule
Emp. Form.C20H25N3O2
Mol. Mass.339.4314
SMILESCOc1ccc(cc1)C1CCCN(C1)C(=O)c1ccnc(c1)N(C)C
Structure
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