| Reaction Details |
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 | Report a problem with these data |
| Target | Prokineticin receptor 1 |
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| Ligand | BDBM347592 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Assay |
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| IC50 | 730±n/a nM |
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| Citation |  Bousba, S; Goldby, A; Jenkins, K; Kinsella, N; Teall, M Piperidine and azepine derivatives as prokineticin receptor modulators US Patent US9790201 Publication Date 10/17/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prokineticin receptor 1 |
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| Name: | Prokineticin receptor 1 |
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| Synonyms: | G-protein coupled receptor 73 | G-protein coupled receptor ZAQ | GPR73 | GPR73a | PK-R1 | PKR1 | PKR1_HUMAN | PROKR1 |
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| Type: | enzyme |
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| Mol. Mass.: | 44779.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TCW9 |
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| Residue: | 393 |
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| Sequence: | METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
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| BDBM347592 |
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| n/a |
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| Name | BDBM347592 |
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| Synonyms: | 3-(Azetidin-1-yl)-5-({3-[4-chloro-2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)pyridazine | US9790201, 77 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20ClF3N4O |
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| Mol. Mass. | 424.847 |
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| SMILES | FC(F)(F)c1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(c1)N1CCC1 |
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| Structure | 
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