| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
|---|
| Ligand | BDBM348670 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Binding Assay |
|---|
| IC50 | 164±n/a nM |
|---|
| Citation |  Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives US Patent US9790230 Publication Date 10/17/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Trace amine-associated receptor 1 |
|---|
| Name: | Trace amine-associated receptor 1 |
|---|
| Synonyms: | TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 38034.73 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q923Y9 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
|
|
|
|---|
| BDBM348670 |
|---|
| n/a |
|---|
| Name | BDBM348670 |
|---|
| Synonyms: | 4-(Cyclopropylmethoxy)-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]benzamide | US9790230, Example 32 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H24N2O3 |
|---|
| Mol. Mass. | 364.4376 |
|---|
| SMILES | O=C(Nc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2)c1ccc(OCC2CC2)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
