| Reaction Details |
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 | Report a problem with these data |
| Target | Tryptase beta-2 |
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| Ligand | BDBM16305 |
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| Substrate/Competitor | BDBM12679 |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| Ki | 28800±n/a nM |
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| Citation |  Katz, BA; Clark, JM; Finer-Moore, JS; Jenkins, TE; Johnson, CR; Ross, MJ; Luong, C; Moore, WR; Stroud, RM Design of potent selective zinc-mediated serine protease inhibitors. Nature391:608-12 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tryptase beta-2 |
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| Name: | Tryptase beta-2 |
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| Synonyms: | TPS2 | TPSB2 | TRYB2_HUMAN | Tryptase | Tryptase II | Tryptase beta-1 | Tryptase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30518.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_210702 |
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| Residue: | 275 |
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| Sequence: | MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
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| BDBM16305 |
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| BDBM12679 |
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| Name | BDBM16305 |
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| Synonyms: | 2-(1H-imidazol-2-ylmethyl)-1H-1,3-benzodiazole-6-carboximidamide | 2-(1H-imidazol-2-ylmethyl)-1H-benzimidazole-6-carboximidamide | APD-3 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N6 |
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| Mol. Mass. | 240.2639 |
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| SMILES | NC(=N)c1ccc2nc(Cc3ncc[nH]3)[nH]c2c1 |
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| Structure | 
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