Reaction Details |
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Target | Prostaglandin D2 receptor 2 |
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Ligand | BDBM234937 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Binding Inhibition Assay (4% HSA) |
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pH | 7.4±n/a |
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Temperature | 298.15±n/a K |
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EC50 | 25.6±n/a nM |
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Comments | extracted |
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Citation | Burgess, LE; Clark, CT; Cook, A; Corrette, CP; DeLisle, RK; Doherty, GA; Hunt, KW; Romoff, TT; Kim, G 6-substituted phenoxychroman carboxylic acid derivatives US Patent US9556139 Publication Date 1/31/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin D2 receptor 2 |
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Name: | Prostaglandin D2 receptor 2 |
Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) |
Type: | Enzyme |
Mol. Mass.: | 43295.45 |
Organism: | Homo sapiens (Human) |
Description: | Q9Y5Y4 |
Residue: | 395 |
Sequence: | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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BDBM234937 |
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n/a |
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Name | BDBM234937 |
Synonyms: | US9556139, 237 Enantiomer 2 |
Type | Small organic molecule |
Emp. Form. | C26H23Cl2NO6 |
Mol. Mass. | 516.37 |
SMILES | COc1cc(Cl)ccc1CCNC(=O)c1ccc(Oc2cc3OCC[C@@H](C(O)=O)c3cc2Cl)cc1 |r| |
Structure |
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