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TargetHDAC4
LigandBDBM243123
Substrate/Competitorn/a
Meas. Tech.HDAC4 Biochemical Assay
IC50 14.0±n/a nM
Citation Maillard MCBreccia PDominguez CHaughan AFVan de Poël AStott AJLuckhurst CASaville-Stones EAWishart GWall MJarvis RE Histone deacetylase inhibitors and compositions and methods of use thereof US Patent  US10053434 Publication Date 8/21/2018
More Info.:Get all data from this article,  Assay Method
 
HDAC4
Name:HDAC4
Synonyms:Histone deacetylase 4
Type:Enzyme
Mol. Mass.:41490.90
Organism:Homo sapiens (Human)
Description:n/a
Residue:385
Sequence:
TKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKAT
LEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHS
AGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQ
RLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVG
FNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYN
LSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQ
RPNANAVRSMEKVMEIHSKYWRCLQ
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  Blast E-value cutoff:
BDBM243123
n/a
NameBDBM243123
Synonyms:(R)-N-(1-(3-Phenylazetidin-1-yl)propan- 2-yl)-4-(5-(trifluoromethyl)-1,2,4- oxadiazol-3-yl)benzamide | US10053434, 8
TypeSmall organic molecule
Emp. Form.C22H21F3N4O2
Mol. Mass.430.4229
SMILESC[C@H](CN1CC(C1)c1ccccc1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r|
Structure
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