| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-glucosidase MAL32 |
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| Ligand | BDBM23840 |
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| Substrate/Competitor | BDBM23837 |
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| Meas. Tech. | alpha-Glucosidase Inhibition Assay |
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| pH | 7±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 16200±n/a nM |
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| Citation |  Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y Co-existence of alpha-glucosidase-inhibitory and liver X receptor-regulatory activities and their separation by structural development. Bioorg Med Chem16:4272-85 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Alpha-glucosidase MAL32 |
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| Name: | Alpha-glucosidase MAL32 |
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| Synonyms: | Alpha-glucosidase MAL32 | MAL32 | MAL32_YEAST | MAL3S | Maltase | alpha-Glucosidase (α-Glucosidase) | alpha-Glucosidase (alpha-Glu) | alpha-Glucosidase (α-Glucosidase) |
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| Type: | Hydrolase |
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| Mol. Mass.: | 68132.36 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | Purchased from Wako Fine Chemicals Co. Ltd. |
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| Residue: | 584 |
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| Sequence: | MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCP
FYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFK
ESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASR
QVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHP
NWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF
THVELGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADD
SPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSF
GKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQ
ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNF
SGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
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| BDBM23840 |
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| BDBM23837 |
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| Name | BDBM23840 |
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| Synonyms: | 2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindole-1,3-dione | CHEMBL246144 | PP2P |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17NO2 |
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| Mol. Mass. | 327.3759 |
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| SMILES | O=C1N(C(=O)c2ccccc12)c1ccccc1CCc1ccccc1 |
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| Structure | 
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