| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NAD(P)H dehydrogenase [quinone] 1 |
|---|
| Ligand | BDBM381902 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | BEAS-2B NQO1 MTT Assay |
|---|
| EC50 | <1±n/a nM |
|---|
| Citation |  Kerns, JK; Callahan, JF; Yan, H; Heightman, TD; Boehm, JC; Woolford, AJ NRF2 regulators US Patent US10272095 Publication Date 4/30/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NAD(P)H dehydrogenase [quinone] 1 |
|---|
| Name: | NAD(P)H dehydrogenase [quinone] 1 |
|---|
| Synonyms: | Azoreductase | DIA4 | DT-diaphorase | Menadione reductase | NAD(P)H:quinone oxidoreductase 1 | NMOR1 | NQO1 | NQO1_HUMAN | Phylloquinone reductase | QR1 | Quinone Reductase 1 | Quinone reductase 1) |
|---|
| Type: | Homodimer |
|---|
| Mol. Mass.: | 30874.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 274 |
|---|
| Sequence: | MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
|
|
|
|---|
| BDBM381902 |
|---|
| n/a |
|---|
| Name | BDBM381902 |
|---|
| Synonyms: | US10272095, Example 67 | rac-(R)-3-(1,4-Dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(rac-(S)-3-(2,2-dimethyl-2,3-dihydropyrido[2,34][1,4]oxazepin-4(5H)-yl)-2,3-dihydro-1H-inden-5-yl)-2,2-dimethylpropanoic Acid, Trifluoroacetic Acid Salt |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H37N5O3 |
|---|
| Mol. Mass. | 539.6679 |
|---|
| SMILES | Cc1c(ccc2n(C)nnc12)[C@H](c1ccc2CC[C@@H](N3Cc4ncccc4OC(C)(C)C3)c2c1)C(C)(C)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
