| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 4 |
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| Ligand | BDBM384313 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | GPR120 pERK assay |
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| EC50 | 80.0±n/a nM |
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| Citation |  Shi, Y; Cheng, PT; Wang, Y; Jusuf, S; Tao, S; Zhang, H; Wu, SC; Robl, JA Cyclopropanecarboxylic acid GPR120 modulators US Patent US9938222 Publication Date 4/10/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 4 |
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| Name: | Free fatty acid receptor 4 |
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| Synonyms: | FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42256.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508994 |
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| Residue: | 377 |
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| Sequence: | MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA
RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI
LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA
ILTDTSVKRNDLSIISG
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| BDBM384313 |
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| n/a |
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| Name | BDBM384313 |
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| Synonyms: | (1R,2R)-2-(((2′,3-Difluoro-5′-phenoxy-[1,1′-biphenyl]-4-yl)oxy)methyl) cyclopropanecarboxylic acid (Enantiomer 1; absolute stereochemistry drawn in an arbitrary manner) | US9938222, Example 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H18F2O4 |
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| Mol. Mass. | 396.3834 |
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| SMILES | OC(=O)[C@@H]1C[C@H]1COc1ccc(cc1F)-c1cc(Oc2ccccc2)ccc1F |r| |
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| Structure | 
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