| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase D |
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| Ligand | BDBM394273 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| IC50 | <10000±n/a nM |
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| Citation |  Jorand-Lebrun, C; Johnson, TL; Graedler, U; Jiang, X; Kulkarni, S Compounds for the inhibition of cyclophilins and uses thereof US Patent US9975902 Publication Date 5/22/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase D |
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| Name: | Peptidyl-prolyl cis-trans isomerase D |
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| Synonyms: | 40 kDa peptidyl-prolyl cis-trans isomerase | CYP-40 | CYP40 | CYPD | Cyclophilin D (CypD) | Cyclophilin-40 | Cyclophilin-related protein | PPID | PPID_HUMAN | PPIase D | Peptidyl-prolyl cis-trans isomerase D | Rotamase D |
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| Type: | Protein |
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| Mol. Mass.: | 40766.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q08752 |
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| Residue: | 370 |
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| Sequence: | MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGH
TTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSM
ANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAE
CGELKEGDDGGIFPKDGSGDSHPDFPEDADIDLKDVDKILLITEDLKNIGNTFFKSQNWE
MAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEAL
ELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDK
EKAVYAKMFA
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| BDBM394273 |
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| n/a |
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| Name | BDBM394273 |
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| Synonyms: | US9975902, Example 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27N3O5 |
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| Mol. Mass. | 425.4776 |
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| SMILES | O[C@@H]1COC2C[C@H]1Nc1ccc(CNC(=O)CN3C(=O)[C@H]4[C@H]5CC[C@H](C5)[C@H]4C3=O)cc21 |r| |
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| Structure | 
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