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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 7 | ||
| Ligand | BDBM29565 | ||
| Substrate/Competitor | BDBM21392 | ||
| Meas. Tech. | Radioligand Binding Assay (Ki) | ||
| pH | 7.4±n/a | ||
| Temperature | 310.15±n/a K | ||
| Ki | 335±22 nM | ||
| Citation |  Paluchowska, MH; Bugno, R; Duszyńska, B; Tatarczyńska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines. Bioorg Med Chem15:7116-25 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| 5-hydroxytryptamine receptor 7 | |||
| Name: | 5-hydroxytryptamine receptor 7 | ||
| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 53573.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34969 | ||
| Residue: | 479 | ||
| Sequence: |
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| BDBM29565 | |||
| BDBM21392 | |||
| Name | BDBM29565 | ||
| Synonyms: | 1-(m-trifluorophenyl)piperazine, 12 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H30F3N3O2 | ||
| Mol. Mass. | 461.5198 | ||
| SMILES | FC(F)(F)c1cccc(c1)N1CCN(CC1)C1CCC(CC1)N1C(=O)C2CC=CCC2C1=O |c:30,(9.97,11.47,;11.29,10.68,;12.06,12.02,;12.62,9.9,;10.5,9.37,;11.24,8.02,;10.45,6.7,;8.91,6.73,;8.16,8.08,;8.96,9.39,;6.62,8.08,;5.82,9.39,;4.28,9.34,;3.54,7.99,;4.35,6.68,;5.89,6.72,;2,7.99,;1.23,9.32,;-.31,9.32,;-1.08,7.99,;-.31,6.65,;1.23,6.65,;-2.62,7.99,;-3.52,9.23,;-3.12,10.72,;-4.99,8.76,;-6.32,9.53,;-7.65,8.75,;-7.65,7.21,;-6.32,6.45,;-4.98,7.22,;-3.52,6.74,;-3.12,5.25,)| | ||
| Structure | 
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