Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 7 | ||
| Ligand | BDBM29567 | ||
| Substrate/Competitor | BDBM21392 | ||
| Meas. Tech. | Radioligand Binding Assay (Ki) | ||
| pH | 7.4±n/a | ||
| Temperature | 310.15±n/a K | ||
| Ki | >5000±n/a nM | ||
| Citation |  Paluchowska, MH; Bugno, R; Duszyńska, B; Tatarczyńska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines. Bioorg Med Chem15:7116-25 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| 5-hydroxytryptamine receptor 7 | |||
| Name: | 5-hydroxytryptamine receptor 7 | ||
| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 53573.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34969 | ||
| Residue: | 479 | ||
| Sequence: |
| ||
| BDBM29567 | |||
| BDBM21392 | |||
| Name | BDBM29567 | ||
| Synonyms: | 1-(m-trifluorophenyl)piperazine, 14 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H28F3N3O2 | ||
| Mol. Mass. | 435.4825 | ||
| SMILES | CC1=C(C)C(=O)N(C2CCC(CC2)N2CCN(CC2)c2cccc(c2)C(F)(F)F)C1=O |c:1,(-6.6,7.5,;-5.1,7.88,;-4.69,9.37,;-5.77,10.47,;-3.15,9.43,;-2.38,10.77,;-2.62,7.99,;-1.08,7.99,;-.31,9.32,;1.23,9.32,;2,7.99,;1.23,6.65,;-.31,6.65,;3.54,7.99,;4.28,9.34,;5.82,9.39,;6.62,8.08,;5.89,6.72,;4.35,6.68,;8.16,8.08,;8.91,6.73,;10.45,6.7,;11.24,8.02,;10.5,9.37,;8.96,9.39,;11.29,10.68,;9.97,11.47,;12.06,12.02,;12.62,9.9,;-3.82,7.03,;-3.82,5.49,)| | ||
| Structure | 
| ||