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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Alpha-1B adrenergic receptor | ||
| Ligand | BDBM29559 | ||
| Substrate/Competitor | BDBM29568 | ||
| Meas. Tech. | Radioligand Binding Assay (Ki) | ||
| Ki | 268±n/a nM | ||
| Citation |  Paluchowska, MH; Bugno, R; Duszyńska, B; Tatarczyńska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines. Bioorg Med Chem15:7116-25 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Alpha-1B adrenergic receptor | |||
| Name: | Alpha-1B adrenergic receptor | ||
| Synonyms: | ADA1B_RAT | Adra1b | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha adrenergic receptor 1A and 1B | Alpha-1 Adrenergic Receptor | Alpha-1Adrenoceptor | Alpha-1B adrenergic receptor | Alpha-1B adrenoreceptor | adrenergic Alpha1B | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 56606.71 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Receptor binding assays were performed using rat cortical membranes. | ||
| Residue: | 515 | ||
| Sequence: |
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| BDBM29559 | |||
| BDBM29568 | |||
| Name | BDBM29559 | ||
| Synonyms: | 1-(m-trifluorophenyl)piperazine, 6 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H32F3N3O2 | ||
| Mol. Mass. | 451.525 | ||
| SMILES | CC1(C)CC(=O)N(C2CCC(CC2)N2CCN(CC2)c2cccc(c2)C(F)(F)F)C(=O)C1 |(-6.78,6.79,;-5.69,7.88,;-6.78,8.97,;-4.97,9.24,;-3.43,9.3,;-2.66,10.63,;-2.62,7.99,;-1.08,7.99,;-.31,9.32,;1.23,9.32,;2,7.99,;1.23,6.65,;-.31,6.65,;3.54,7.99,;4.28,9.34,;5.82,9.39,;6.62,8.08,;5.89,6.72,;4.35,6.68,;8.16,8.08,;8.91,6.73,;10.45,6.7,;11.24,8.02,;10.5,9.37,;8.96,9.39,;11.29,10.68,;9.97,11.47,;12.06,12.02,;12.62,9.9,;-3.34,6.63,;-2.57,5.3,;-4.88,6.58,)| | ||
| Structure | 
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