| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM36328 |
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| Substrate/Competitor | BDBM36388 |
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| Meas. Tech. | Assay name: Protease Inhibition Assay |
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| pH | 5.5±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 15±n/a nM |
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| Citation |  Kato, D; Boatright, KM; Berger, AB; Nazif, T; Blum, G; Ryan, C; Chehade, KA; Salvesen, GS; Bogyo, M Activity-based probes that target diverse cysteine protease families. Nat Chem Biol1:33-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | CATB_RAT | Ctsb |
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| Type: | Protein |
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| Mol. Mass.: | 37463.53 |
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| Organism: | Rattus norvegicus |
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| Description: | P00787 |
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| Residue: | 339 |
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| Sequence: | MWWSLIPLSCLLALTSAHDKPSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG
TVLGGPNLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDR
ICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCL
PYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIM
AEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSW
NVDWGDNGFFKILRGENHCGIESEIVAGIPRTQQYWGRF
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| BDBM36328 |
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| BDBM36388 |
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| Name | BDBM36328 |
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| Synonyms: | Z-FR-AMOK 9b |
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| Type | Small organic molecule |
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| Emp. Form. | C33H39N5O6 |
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| Mol. Mass. | 601.6927 |
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| SMILES | [#6]-c1cccc(-[#6])c1-[#6](=O)-[#8]-[#6]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1 |
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| Structure | 
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