| Reaction Details |
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 | Report a problem with these data |
| Target | 3C-like protease |
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| Ligand | BDBM47871 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) |
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| IC50 | 5098±n/a nM |
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| Citation |  PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 3C-like protease |
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| Name: | 3C-like protease |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 33462.05 |
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| Organism: | Avian infectious bronchitis virus |
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| Description: | gi_73745819 |
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| Residue: | 307 |
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| Sequence: | SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANN
HEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTV
IGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFY
GGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASD
NGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQ
VGGVRLQ
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| BDBM47871 |
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| n/a |
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| Name | BDBM47871 |
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| Synonyms: | 4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]carbonyl-1H-quinolin-2-one | 4-[4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl]-1H-quinolin-2-one | 4-[4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl]carbostyril | 4-[oxo-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]methyl]-1H-quinolin-2-one | CVD-0013258 | ERI-UCB-a0b0dbcb-4 | MLS000760808 | SMR000370919 | cid_2449860 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18F3N3O2 |
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| Mol. Mass. | 401.3817 |
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| SMILES | FC(F)(F)c1cccc(c1)N1CCN(CC1)C(=O)c1cc(=O)[nH]c2ccccc12 |
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| Structure | 
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