| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Capsid scaffolding protein |
|---|
| Ligand | BDBM59214 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Competitive Assay |
|---|
| pH | 5.52±0 |
|---|
| Ki | 3.0e+3± 1e+2 nM |
|---|
| IC50 | 5.9e+3± 5e+2 nM |
|---|
| Citation |  Bowman, MJ; Byrne, S; Chmielewski, J Switching between allosteric and dimerization inhibition of HIV-1 protease. Chem Biol12:439-44 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Capsid scaffolding protein |
|---|
| Name: | Capsid scaffolding protein |
|---|
| Synonyms: | Human herpesvirus 1 protease | SCAF_HHV11 | UL26 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66472.05 |
|---|
| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
|---|
| Description: | ChEMBL_158648 |
|---|
| Residue: | 635 |
|---|
| Sequence: | MAADAPGDRMEEPLPDRAVPIYVAGFLALYDSGDSGELALDPDTVRAALPPDNPLPINVD
HRAGCEVGRVLAVVDDPRGPFFVGLIACVQLERVLETAASAAIFERRGPPLSREERLLYL
ITNYLPSVSLATKRLGGEAHPDRTLFAHVALCAIGRRLGTIVTYDTGLDAAIAPFRHLSP
ASREGARRLAAEAELALSGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIA
GHTYLQASEKFKMWGAEPVSAPARGYKNGAPESTDIPPGSIAAAPQGDRCPIVRQRGVAL
SPVLPPMNPVPTSGTPAPAPPGDGSYLWIPASHYNQLVAGHAAPQPQPHSAFGFPAAAGS
VAYGPHGAGLSQHYPPHVAHQYPGVLFSGPSPLEAQIAALVGAIAADRQAGGQPAAGDPG
VRGSGKRRRYEAGPSESYCDQDEPDADYPYYPGEARGAPRGVDSRRAARHSPGTNETITA
LMGAVTSLQQELAHMRARTSAPYGMYTPVAHYRPQVGEPEPTTTHPALCPPEAVYRPPPH
SAPYGPPQGPASHAPTPPYAPAACPPGPPPPPCPSTQTRAPLPTEPAFPPAATGSQPEAS
NAEAGALVNASSAAHVDVDTARAADLFVSQMMGAR
|
|
|
|---|
| BDBM59214 |
|---|
| n/a |
|---|
| Name | BDBM59214 |
|---|
| Synonyms: | Pepstatin analog, 2 |
|---|
| Type | Peptide |
|---|
| Emp. Form. | C48H73N7O10 |
|---|
| Mol. Mass. | 908.1341 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@@H](NC(=O)CCCCCCCCCCCCCCC(=O)N[C@H](CC(N)=O)C(=O)N[C@H](Cc1ccccc1)C(O)=O)C(C)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
