| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM59224 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Zhang-Poorman Assay |
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| pH | 5.52±0 |
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| Ki | 96±10 nM |
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| IC50 | 3.6e+2± 3e+1 nM |
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| Citation |  Bowman, MJ; Byrne, S; Chmielewski, J Switching between allosteric and dimerization inhibition of HIV-1 protease. Chem Biol12:439-44 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | Human herpesvirus 1 protease | SCAF_HHV11 | UL26 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66472.05 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | ChEMBL_158648 |
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| Residue: | 635 |
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| Sequence: | MAADAPGDRMEEPLPDRAVPIYVAGFLALYDSGDSGELALDPDTVRAALPPDNPLPINVD
HRAGCEVGRVLAVVDDPRGPFFVGLIACVQLERVLETAASAAIFERRGPPLSREERLLYL
ITNYLPSVSLATKRLGGEAHPDRTLFAHVALCAIGRRLGTIVTYDTGLDAAIAPFRHLSP
ASREGARRLAAEAELALSGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIA
GHTYLQASEKFKMWGAEPVSAPARGYKNGAPESTDIPPGSIAAAPQGDRCPIVRQRGVAL
SPVLPPMNPVPTSGTPAPAPPGDGSYLWIPASHYNQLVAGHAAPQPQPHSAFGFPAAAGS
VAYGPHGAGLSQHYPPHVAHQYPGVLFSGPSPLEAQIAALVGAIAADRQAGGQPAAGDPG
VRGSGKRRRYEAGPSESYCDQDEPDADYPYYPGEARGAPRGVDSRRAARHSPGTNETITA
LMGAVTSLQQELAHMRARTSAPYGMYTPVAHYRPQVGEPEPTTTHPALCPPEAVYRPPPH
SAPYGPPQGPASHAPTPPYAPAACPPGPPPPPCPSTQTRAPLPTEPAFPPAATGSQPEAS
NAEAGALVNASSAAHVDVDTARAADLFVSQMMGAR
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| BDBM59224 |
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| n/a |
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| Name | BDBM59224 |
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| Synonyms: | Pepstatin analog, 12 |
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| Type | Peptide |
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| Emp. Form. | C53H76N6O11 |
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| Mol. Mass. | 973.2041 |
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| SMILES | CC(C)C[C@@H](NC(=O)[C@H](NC(=O)CCCCCCCCCCCCCCC(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O)C(C)O)C(=O)NCCc1ccc(Oc2ccc(O)cc2)cc1 |r| |
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| Structure | 
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