| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 2 |
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| Ligand | BDBM81510 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorogenic Assay |
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| pH | 8±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 7.0e+3± 4e+2 nM |
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| Citation |  Albrow, VE; Ponder, EL; Fasci, D; Békés, M; Deu, E; Salvesen, GS; Bogyo, M Development of small molecule inhibitors and probes of human SUMO deconjugating proteases. Chem Biol18:722-32 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sentrin-specific protease 2 |
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| Name: | Sentrin-specific protease 2 |
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| Synonyms: | KIAA1331 | SENP2 | SENP2_HUMAN | Sentrin-specific protease 2 (SENP2) |
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| Type: | Protein |
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| Mol. Mass.: | 67890.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9HC62 |
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| Residue: | 589 |
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| Sequence: | MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVK
NSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLG
NKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKP
QEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYH
SSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTE
TMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDR
RTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYM
NLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWS
LVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIP
QQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
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| BDBM81510 |
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| n/a |
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| Name | BDBM81510 |
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| Synonyms: | JCP-666 |
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| Type | Small organic molecule |
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| Emp. Form. | C44H36N4O9 |
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| Mol. Mass. | 764.778 |
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| SMILES | OC(=O)CN(NC(=O)c1ccc(CNC(=O)c2cccc(c2)C(O)=O)cc1)C(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12 |r| |
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| Structure | 
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