| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 2 |
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| Ligand | BDBM271163 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Ca-Flux Functional Assay |
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| EC50 | 1.000±n/a nM |
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| Citation |  Barker, G; Davenport, R; Downham, R; Farnaby, W; Goldby, A; Hannah, D; Harrison, D; Willems, H 3-substituted 2-amino-indole derivatives US Patent US10059713 Publication Date 8/28/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 2 |
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| Name: | Free fatty acid receptor 2 |
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| Synonyms: | FFA2 | FFAR2 | FFAR2_HUMAN | G-protein coupled receptor 43 | GPCR43 | GPR43 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37156.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508993 |
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| Residue: | 330 |
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| Sequence: | MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR
LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV
SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG
RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
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| BDBM271163 |
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| n/a |
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| Name | BDBM271163 |
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| Synonyms: | 7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(2S)-2-(trifluoromethyl)morpholin-4-yl]-5H-pyrrolo[3,2-d]pyrimidin-6-amine | US10059713, Example 284 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16ClF4N5O3S |
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| Mol. Mass. | 493.863 |
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| SMILES | Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccc(Cl)cc1F |r| |
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| Structure | 
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