| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nucleoside diphosphate kinase B |
|---|
| Ligand | BDBM50240746 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1668651 (CHEMBL4018539) |
|---|
| Kd | 16100±n/a nM |
|---|
| Citation |  Wang, YQ; Huang, ZL; Chen, SB; Wang, CX; Shan, C; Yin, QK; Ou, TM; Li, D; Gu, LQ; Tan, JH; Huang, ZS Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction. J Med Chem60:6924-6941 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nucleoside diphosphate kinase B |
|---|
| Name: | Nucleoside diphosphate kinase B |
|---|
| Synonyms: | 2.7.13.3 | 2.7.4.6 | C-myc purine-binding transcription factor PUF | Histidine protein kinase NDKB | NDK B | NDKB_HUMAN | NDP kinase B | NM23B | NME2 | Nucleoside diphosphate kinase B | nm23-H2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 17301.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_10050 |
|---|
| Residue: | 152 |
|---|
| Sequence: | MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
|
|
|
|---|
| BDBM50240746 |
|---|
| n/a |
|---|
| Name | BDBM50240746 |
|---|
| Synonyms: | CHEMBL4086337 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H31FN4O3 |
|---|
| Mol. Mass. | 514.5905 |
|---|
| SMILES | CN(C)CCCNc1cc2nc3\C(CCn3c(=O)c2cc1F)=C\c1ccc(OCc2ccccc2)c(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
