| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleoside diphosphate kinase B |
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| Ligand | BDBM50240753 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1668650 (CHEMBL4018538) |
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| Kd | 15800±n/a nM |
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| Citation |  Wang, YQ; Huang, ZL; Chen, SB; Wang, CX; Shan, C; Yin, QK; Ou, TM; Li, D; Gu, LQ; Tan, JH; Huang, ZS Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction. J Med Chem60:6924-6941 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nucleoside diphosphate kinase B |
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| Name: | Nucleoside diphosphate kinase B |
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| Synonyms: | 2.7.13.3 | 2.7.4.6 | C-myc purine-binding transcription factor PUF | Histidine protein kinase NDKB | NDK B | NDKB_HUMAN | NDP kinase B | NM23B | NME2 | Nucleoside diphosphate kinase B | nm23-H2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17301.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_10050 |
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| Residue: | 152 |
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| Sequence: | MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPF
FPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
DSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
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| BDBM50240753 |
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| n/a |
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| Name | BDBM50240753 |
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| Synonyms: | CHEMBL4066570 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29FN4O3 |
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| Mol. Mass. | 452.5212 |
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| SMILES | COc1ccc(\C=C2/CCn3c2nc2cc(NCCCN(C)C)c(F)cc2c3=O)cc1OC |
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| Structure | 
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