| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50240950 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1669357 (CHEMBL4019245) |
|---|
| Ki | 16±n/a nM |
|---|
| Citation |  Erli, F; Guerrieri, E; Ben Haddou, T; Lantero, A; Mairegger, M; Schmidhammer, H; Spetea, M Highly Potent and Selective New Diphenethylamines Interacting with the?-Opioid Receptor: Synthesis, Pharmacology, and Structure-Activity Relationships. J Med Chem60:7579-7590 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50240950 |
|---|
| n/a |
|---|
| Name | BDBM50240950 |
|---|
| Synonyms: | CHEMBL4094512 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H28ClNO2 |
|---|
| Mol. Mass. | 361.906 |
|---|
| SMILES | Cl.Oc1ccc(CCN(CCc2cccc(O)c2)CC2CCC2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
