| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50240950 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1669358 (CHEMBL4019246) |
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| Ki | 428±n/a nM |
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| Citation |  Erli, F; Guerrieri, E; Ben Haddou, T; Lantero, A; Mairegger, M; Schmidhammer, H; Spetea, M Highly Potent and Selective New Diphenethylamines Interacting with the?-Opioid Receptor: Synthesis, Pharmacology, and Structure-Activity Relationships. J Med Chem60:7579-7590 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50240950 |
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| n/a |
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| Name | BDBM50240950 |
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| Synonyms: | CHEMBL4094512 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28ClNO2 |
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| Mol. Mass. | 361.906 |
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| SMILES | Cl.Oc1ccc(CCN(CCc2cccc(O)c2)CC2CCC2)cc1 |
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| Structure | 
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