| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50003392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_36783 |
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| IC50 | 16±n/a nM |
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| Citation |  Bradbury, RH; Allott, CP; Dennis, M; Fisher, E; Major, JS; Masek, BB; Oldham, AA; Pearce, RJ; Rankine, N; Revill, JM New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)quinoline derivatives. J Med Chem35:4027-38 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_CAVPO | AT1 | Angiotensin II type-1 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41004.19 |
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| Organism: | Cavia porcellus |
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| Description: | ChEMBL_36783 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE
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| BDBM50003392 |
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| n/a |
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| Name | BDBM50003392 |
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| Synonyms: | 2-Methyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-quinoline | 2-Methyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-quinoline | CHEMBL142380 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H19N5O |
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| Mol. Mass. | 393.4406 |
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| SMILES | Cc1cc(OCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2ccccc2n1 |
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| Structure | 
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