| Reaction Details |
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 | Report a problem with these data |
| Target | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Ligand | BDBM50249990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1680835 |
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| Kd | 8.0±n/a nM |
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| Citation |  Jiang, Y; Zhuang, C; Chen, L; Lu, J; Dong, G; Miao, Z; Zhang, W; Li, J; Sheng, C Structural Biology-Inspired Discovery of Novel KRAS-PDE? Inhibitors. J Med Chem60:9400-9406 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Name: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Synonyms: | 3',5'-cyclic phosphodiesterase | GMP-PDE delta | PDE6D | PDE6D_HUMAN | PDED | Protein p17 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17418.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_105761 |
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| Residue: | 150 |
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| Sequence: | MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
SVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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| BDBM50249990 |
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| n/a |
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| Name | BDBM50249990 |
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| Synonyms: | CHEMBL4090022 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H30F2N4O2 |
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| Mol. Mass. | 552.6137 |
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| SMILES | Fc1ccccc1C1Nc2ccccc2C(=O)N1CCCCCN1C(Nc2ccccc2C1=O)c1ccccc1F |
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| Structure | 
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