| Reaction Details |
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 | Report a problem with these data |
| Target | ELAV-like protein 1 |
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| Ligand | BDBM50269996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1707813 (CHEMBL4059046) |
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| Ki | 81±n/a nM |
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| Citation |  Manzoni, L; Zucal, C; Maio, DD; D'Agostino, VG; Thongon, N; Bonomo, I; Lal, P; Miceli, M; Baj, V; Brambilla, M; Cerofolini, L; Elezgarai, S; Biasini, E; Luchinat, C; Novellino, E; Fragai, M; Marinelli, L; Provenzani, A; Seneci, P Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors. J Med Chem61:1483-1498 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| ELAV-like protein 1 |
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| Name: | ELAV-like protein 1 |
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| Synonyms: | ELAV1_HUMAN | ELAVL1 | HUR | Hu-antigen R |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36102.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_654855 |
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| Residue: | 326 |
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| Sequence: | MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS
LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK
DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPIT
VKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNA
SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM
AIASLNGYRLGDKILQVSFKTNKSHK
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| BDBM50269996 |
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| n/a |
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| Name | BDBM50269996 |
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| Synonyms: | CHEMBL4094161 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H16N2O5S |
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| Mol. Mass. | 420.438 |
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| SMILES | CC(=O)Nc1ccc(cc1)S(=O)(=O)n1cc(c2c1C=CC(=O)C2=O)-c1ccccc1 |c:20| |
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| Structure | 
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