Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270003 (CHEMBL4075458) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269995 (CHEMBL4064932) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 3 (Homo sapiens (Human)) | BDBM13211 ((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 25 | -43.1 | 460 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Universita degli Studi di Milano | Assay Description Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e... | Bioorg Med Chem 17: 5834-56 (2009) Article DOI: 10.1016/j.bmc.2009.07.009 BindingDB Entry DOI: 10.7270/Q28W3BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269992 (CHEMBL4095060) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269999 (CHEMBL4100171) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50423877 (DIHYDROTANSHINONE | Dihydrotanshinone I | acs.jmed...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269991 (CHEMBL4105230) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270012 (CHEMBL4073526) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 3 (Homo sapiens (Human)) | BDBM13212 ((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 61 | -40.9 | 530 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Universita degli Studi di Milano | Assay Description Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e... | Bioorg Med Chem 17: 5834-56 (2009) Article DOI: 10.1016/j.bmc.2009.07.009 BindingDB Entry DOI: 10.7270/Q28W3BNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269996 (CHEMBL4094161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269994 (CHEMBL4102819) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270013 (CHEMBL4081086) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270014 (CHEMBL4076484) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270007 (CHEMBL4067653) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid UniChem Similars | Article PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269997 (CHEMBL4092808) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270002 (CHEMBL4077265) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | >200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270001 (CHEMBL4075620) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | >200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50269990 (CHEMBL4070465) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human)) | BDBM26205 ((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(2-ami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 220 | -37.6 | 250 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Milano | Assay Description Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e... | J Mol Biol 384: 673-89 (2008) Article DOI: 10.1016/j.jmb.2008.09.064 BindingDB Entry DOI: 10.7270/Q2NG4NZ8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human)) | BDBM26203 ((3S,6S,7S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 250 | -37.3 | 270 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Milano | Assay Description Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e... | J Mol Biol 384: 673-89 (2008) Article DOI: 10.1016/j.jmb.2008.09.064 BindingDB Entry DOI: 10.7270/Q2NG4NZ8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ELAV-like protein 1 (Homo sapiens (Human)) | BDBM50270004 (CHEMBL4073683) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular Science and Technology (ISTM) Curated by ChEMBL | Assay Description Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction... | J Med Chem 61: 1483-1498 (2018) Article DOI: 10.1021/acs.jmedchem.7b01176 BindingDB Entry DOI: 10.7270/Q2Q81GKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human)) | BDBM13211 ((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 420 | -36.0 | 460 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Milano | Assay Description Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e... | J Mol Biol 384: 673-89 (2008) Article DOI: 10.1016/j.jmb.2008.09.064 BindingDB Entry DOI: 10.7270/Q2NG4NZ8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human)) | BDBM26204 ((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(amino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 870 | -34.2 | 970 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Milano | Assay Description Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e... | J Mol Biol 384: 673-89 (2008) Article DOI: 10.1016/j.jmb.2008.09.064 BindingDB Entry DOI: 10.7270/Q2NG4NZ8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50240586 (CHEMBL4098982) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Scienze e Tecnologie Molecolari (ISTM) Curated by ChEMBL | Assay Description Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu... | Bioorg Med Chem Lett 27: 2336-2344 (2017) Article DOI: 10.1016/j.bmcl.2017.04.032 BindingDB Entry DOI: 10.7270/Q2GH9M3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401475 (CHEMBL2205248) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401483 (CHEMBL2204574) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50240587 (CHEMBL4070316) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Scienze e Tecnologie Molecolari (ISTM) Curated by ChEMBL | Assay Description Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu... | Bioorg Med Chem Lett 27: 2336-2344 (2017) Article DOI: 10.1016/j.bmcl.2017.04.032 BindingDB Entry DOI: 10.7270/Q2GH9M3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401484 (CHEMBL2204575) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM32609 (1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Scienze e Tecnologie Molecolari (ISTM) Curated by ChEMBL | Assay Description Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu... | Bioorg Med Chem Lett 27: 2336-2344 (2017) Article DOI: 10.1016/j.bmcl.2017.04.032 BindingDB Entry DOI: 10.7270/Q2GH9M3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401493 (CHEMBL2205246) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50240589 (CHEMBL4091245) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Scienze e Tecnologie Molecolari (ISTM) Curated by ChEMBL | Assay Description Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu... | Bioorg Med Chem Lett 27: 2336-2344 (2017) Article DOI: 10.1016/j.bmcl.2017.04.032 BindingDB Entry DOI: 10.7270/Q2GH9M3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401477 (CHEMBL2204567) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401489 (CHEMBL2204580) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50240592 (CHEMBL4097534) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Scienze e Tecnologie Molecolari (ISTM) Curated by ChEMBL | Assay Description Inhibition of SMAC derived peptide abuRPF-K(5-Fam)-NH2 interaction with recombinant human C-terminal 6His-tagged cIAP1 BIR3 domain (245 to 357 residu... | Bioorg Med Chem Lett 27: 2336-2344 (2017) Article DOI: 10.1016/j.bmcl.2017.04.032 BindingDB Entry DOI: 10.7270/Q2GH9M3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401481 (CHEMBL2204572) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401485 (CHEMBL2204576) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401492 (CHEMBL2204582) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401488 (CHEMBL2204579) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401474 (CHEMBL2205247) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401482 (CHEMBL2204573) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401479 (CHEMBL2204569) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401487 (CHEMBL2204578) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401480 (CHEMBL2204571) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401488 (CHEMBL2204579) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401487 (CHEMBL2204578) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401483 (CHEMBL2204574) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401476 (CHEMBL2205249) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401478 (CHEMBL2204568) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human)) | BDBM50401490 (CHEMBL2204570) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM50401491 (CHEMBL2204581) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione IRCCS Istituto Nazionale dei Tumori Curated by ChEMBL | Assay Description Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assay | Bioorg Med Chem 20: 6709-23 (2012) Article DOI: 10.1016/j.bmc.2012.09.041 BindingDB Entry DOI: 10.7270/Q2P84D2Z | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
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