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TargetVasopressin V2 receptor
LigandBDBM50013640
Substrate/Competitorn/a
Meas. Tech.ChEBML_215028
Ki 49.0±n/a nM
Citation Freidinger, RMWilliams, PDTung, RDBock, MGPettibone, DJClineschmidt, BVDiPardo, RMErb, JMGarsky, VMGould, NP Cyclic hexapeptide oxytocin antagonists. Potency-, selectivity-, and solubility-enhancing modifications. J Med Chem33:1843-5 (1990) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Vasopressin V2 receptor
Name:Vasopressin V2 receptor
Synonyms:AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor
Type:G-protein coupled receptor
Mol. Mass.:40761.85
Organism:Rattus norvegicus (Rat)
Description:n/a
Residue:371
Sequence:
MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
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  Blast E-value cutoff:
BDBM50013640
n/a
NameBDBM50013640
Synonyms:18-(3-Amino-propyl)-15-benzyl-3-sec-butyl-6-(1H-indol-3-ylmethyl)-16-methyl-1,4,7,13,16,19-hexaaza-tricyclo[19.4.0.0*9,13*]pentacosane-2,5,8,14,17,20-hexaone | CHEMBL2372928
TypeSmall organic molecule
Emp. Form.C43H58N8O6
Mol. Mass.782.9706
SMILES[H][C@@]12CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](CCCN)NC(=O)[C@@]1([H])CCCCN1C(=O)[C@]([H])(NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC2=O)[C@H](C)CC
Structure
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