| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50286056 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1728853 (CHEMBL4144131) |
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| EC50 | 6.3±n/a nM |
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| Citation |  Han, S; Thoresen, L; Jung, JK; Zhu, X; Thatte, J; Solomon, M; Gaidarov, I; Unett, DJ; Yoon, WH; Barden, J; Sadeque, A; Usmani, A; Chen, C; Semple, G; Grottick, AJ; Al-Shamma, H; Christopher, R; Jones, RM Discovery of APD371: Identification of a Highly Potent and Selective CB ACS Med Chem Lett8:1309-1313 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39366.68 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9QZN9 |
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| Residue: | 360 |
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| Sequence: | MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
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| BDBM50286056 |
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| n/a |
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| Name | BDBM50286056 |
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| Synonyms: | CHEMBL4172104 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16F3N5O2 |
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| Mol. Mass. | 367.3257 |
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| SMILES | [H][C@@]12C[C@]1([H])c1c(C2)c(nn1-c1c[n+]([O-])ccn1)C(=O)NC(C)(C)C(F)(F)F |r| |
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| Structure | 
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