| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Trace amine-associated receptor 5 |
|---|
| Ligand | BDBM50293273 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1731932 (CHEMBL4147468) |
|---|
| EC50 | >10000±n/a nM |
|---|
| Citation |  Guariento, S; Tonelli, M; Espinoza, S; Gerasimov, AS; Gainetdinov, RR; Cichero, E Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists. Eur J Med Chem146:171-184 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Trace amine-associated receptor 5 |
|---|
| Name: | Trace amine-associated receptor 5 |
|---|
| Synonyms: | Gm227 | TAAR5_MOUSE | TaR-5 | Taar5 | Trace amine receptor 5 | Trace amine-associated receptor 5 | Trimethylamine receptor | mTaar5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38230.08 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_116770 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVS
YFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLT
SIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALS
QWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSL
AGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSAC
NPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
|
|
|
|---|
| BDBM50293273 |
|---|
| n/a |
|---|
| Name | BDBM50293273 |
|---|
| Synonyms: | CHEMBL4172220 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H19Cl3N6 |
|---|
| Mol. Mass. | 353.678 |
|---|
| SMILES | Cl.Cl.NC(=N)\N=C(/N)N1CCN(CC1)c1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
