| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2-macroglobulin |
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| Ligand | BDBM50366669 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1735454 (CHEMBL4150990) |
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| IC50 | 257000±n/a nM |
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| Citation |  Zhang, C; Sun, C; Huang, H; Gui, C; Wang, L; Li, Q; Ju, J Biosynthetic Baeyer-Villiger Chemistry Enables Access to Two Anthracene Scaffolds from a Single Gene Cluster in Deep-Sea-Derived Streptomyces olivaceus SCSIO T05. J Nat Prod81:1570-1577 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2-macroglobulin |
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| Name: | Alpha-2-macroglobulin |
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| Synonyms: | A2M | A2MG_HUMAN | Alpha-2-M | Alpha-2-macroglobulin | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 | CPAMD5 | CPAMD5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 163287.04 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117935 |
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| Residue: | 1474 |
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| Sequence: | MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV
SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV
MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS
FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT
ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF
YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR
QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT
VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY
ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL
LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV
DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSS
TNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARL
VHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGI
SSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVE
KEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVI
KPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQ
NTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKH
YDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCF
RSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDH
GSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQ
APSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHA
LSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEG
CVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAI
VDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVR
DLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA
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| BDBM50366669 |
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| n/a |
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| Name | BDBM50366669 |
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| Synonyms: | CHEMBL4176713 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24O7 |
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| Mol. Mass. | 388.4111 |
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| SMILES | CC(C)CC[C@]1(O)[C@]2(O)[C@@H](C)C(=O)C3=Cc4cccc(O)c4[C@H](O)[C@]13OC2=O |r,t:13,TLB:27:26:13.11.9:5| |
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| Structure | 
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