Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPlatelet activating factor receptor
LigandBDBM50018316
Substrate/Competitorn/a
Meas. Tech.ChEBML_154997
IC50 4±n/a nM
Citation Tilley JWClader JWZawoiski SWirkus MLeMahieu RAO'Donnell MCrowley HWelton AF Biphenylcarboxamide derivatives as antagonists of platelet-activating factor. J Med Chem 32:1814-20 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39219.60
Organism:Homo sapiens (Human)
Description:PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50018316
n/a
NameBDBM50018316
Synonyms:2-Butyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid (1-methyl-4-pyridin-3-yl-butyl)-amide | CHEMBL51692
TypeSmall organic molecule
Emp. Form.C29H36N2O3
Mol. Mass.460.6077
SMILESCCCCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)N[C@H](C)CCCc1cccnc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: