| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
|---|
| Ligand | BDBM50018339 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_154997 (CHEMBL767101) |
|---|
| IC50 | 700±n/a nM |
|---|
| Citation |  Tilley, JW; Clader, JW; Zawoiski, S; Wirkus, M; LeMahieu, RA; O'Donnell, M; Crowley, H; Welton, AF Biphenylcarboxamide derivatives as antagonists of platelet-activating factor. J Med Chem32:1814-20 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Platelet-activating factor receptor |
|---|
| Name: | Platelet-activating factor receptor |
|---|
| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 39219.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
|---|
| Residue: | 342 |
|---|
| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
|
|
|
|---|
| BDBM50018339 |
|---|
| n/a |
|---|
| Name | BDBM50018339 |
|---|
| Synonyms: | 3'-(Cyclohepta-1,3,5-trienyloxy)-biphenyl-4-carboxylic acid (4-pyridin-3-yl-butyl)-amide | CHEMBL50050 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H28N2O2 |
|---|
| Mol. Mass. | 436.5448 |
|---|
| SMILES | O=C(NCCCCc1cccnc1)c1ccc(cc1)-c1cccc(OC2=CC=CC=CC2)c1 |c:29,31,t:27| |
|---|
| Structure | 
|
|---|
Search and Browse
