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TargetPlatelet activating factor receptor
LigandBDBM50018345
Substrate/Competitorn/a
Meas. Tech.ChEBML_154996
IC50 120±n/a nM
Citation Guthrie RWKaplan GLMennona FATilley JWKierstead RWMullin JGLeMahieu RAZawoiski SO'Donnell MCrowley H Pentadienyl carboxamide derivatives as antagonists of platelet-activating factor. J Med Chem 32:1820-35 (1989) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39219.60
Organism:Homo sapiens (Human)
Description:PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50018345
n/a
NameBDBM50018345
Synonyms:5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid (1-ethyl-4-pyridin-3-yl-butyl)-amide | CHEMBL54482
TypeSmall organic molecule
Emp. Form.C30H34N2O3
Mol. Mass.470.6026
SMILES[#6]-[#6]-[#6@H](-[#6]-[#6]-[#6]-c1cccnc1)-[#7]-[#6](=O)\[#6]=[#6]\[#6]=[#6](\c1ccc(-[#8]-[#6])cc1)-c1ccc(-[#8]-[#6])cc1
Structure
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