| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50019722 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_59342 (CHEMBL668766) |
|---|
| Ki | 150±n/a nM |
|---|
| Citation |  Henning, R; Lattrell, R; Gerhards, HJ; Leven, M Synthesis and neuroleptic activity of a series of 1-[1-(benzo-1,4-dioxan-2-ylmethyl)-4-piperidinyl]benzim idazolone derivatives. J Med Chem30:814-9 (1987) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50698.79 |
|---|
| Organism: | BOVINE |
|---|
| Description: | P20288 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50019722 |
|---|
| n/a |
|---|
| Name | BDBM50019722 |
|---|
| Synonyms: | 1-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-5-methoxy-1,3-dihydro-benzoimidazol-2-one | CHEMBL355068 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25N3O4 |
|---|
| Mol. Mass. | 395.4516 |
|---|
| SMILES | COc1ccc2n(C3CCN(CC4COc5ccccc5O4)CC3)c(=O)[nH]c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
