| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50020674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_211260 |
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| Ki | 8.9±n/a nM |
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| Citation |  Yim, NC; Moore, ML; Huffman, WF; Bryan, HG; Chang, HL; Kinter, LB; Edwards, R; Stassen, FL; Schmidt, D; Heckman, G Potent antagonists of vasopressin antidiuretic activity that lack the beta,beta-cyclopentamethylene-beta-mercaptopropionic acid substitution at position 1. J Med Chem29:2425-6 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR2 | V2R_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40556.17 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_214870 |
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| Residue: | 370 |
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| Sequence: | MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGA
LVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMV
GMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQR
DVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPA
ERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATA
SSFSARDTSS
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| BDBM50020674 |
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| n/a |
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| Name | BDBM50020674 |
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| Synonyms: | 1-[13-Benzyl-7-carbamoylmethyl-16-(4-ethoxy-benzyl)-20,20-diethyl-10-isopropyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicosane-4-carbonyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-4-guanidino-butyl)-amide | CHEMBL412392 |
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| Type | Small organic molecule |
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| Emp. Form. | C50H74N12O10S2 |
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| Mol. Mass. | 1067.327 |
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| SMILES | CCOc1ccc(C[C@H]2NC(=O)CC(CC)(CC)SSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](Cc3ccccc3)NC2=O)C(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@H](CCCNC(N)=N)C(N)=O)cc1 |
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| Structure | 
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