| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM60917 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_59312 |
|---|
| IC50 | 1580±n/a nM |
|---|
| Citation |  Weinstock, J; Gaitanopoulos, DE; Stringer, OD; Franz, RG; Hieble, JP; Kinter, LB; Mann, WA; Flaim, KE; Gessner, G Synthesis and evaluation of non-catechol D-1 and D-2 dopamine receptor agonists: benzimidazol-2-one, benzoxazol-2-one, and the highly potent benzothiazol-2-one 7-ethylamines. J Med Chem30:1166-76 (1987) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50698.79 |
|---|
| Organism: | BOVINE |
|---|
| Description: | P20288 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM60917 |
|---|
| n/a |
|---|
| Name | BDBM60917 |
|---|
| Synonyms: | 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid | FENOLDOPAM | FENOLDOPAM MESYLATE | MLS001401388 | SMR000469190 | cid_49659 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H16ClNO3 |
|---|
| Mol. Mass. | 305.756 |
|---|
| SMILES | Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
