| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nicotinamide N-methyltransferase |
|---|
| Ligand | BDBM50455086 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1753837 (CHEMBL4188597) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Ruf, S; Hallur, MS; Anchan, NK; Swamy, IN; Murugesan, KR; Sarkar, S; Narasimhulu, LK; Putta, VPRK; Shaik, S; Chandrasekar, DV; Mane, VS; Kadnur, SV; Suresh, J; Bhamidipati, RK; Singh, M; Burri, RR; Kristam, R; Schreuder, H; Czech, J; Rudolph, C; Marker, A; Langer, T; Mullangi, R; Yura, T; Gosu, R; Kannt, A; Dhakshinamoorthy, S; Rajagopal, S Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase. Bioorg Med Chem Lett28:922-925 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nicotinamide N-methyltransferase |
|---|
| Name: | Nicotinamide N-methyltransferase |
|---|
| Synonyms: | NNMT | NNMT_HUMAN | Nicotinamide N-methyltransferase | Nicotinamide N-methyltransferase (NNMT) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 29571.16 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 264 |
|---|
| Sequence: | MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
SYSSTMANNEGLFSLVARKLSRPL
|
|
|
|---|
| BDBM50455086 |
|---|
| n/a |
|---|
| Name | BDBM50455086 |
|---|
| Synonyms: | CHEMBL4204179 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H8N2O |
|---|
| Mol. Mass. | 136.1512 |
|---|
| SMILES | Cc1ccc(cn1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
