Compile Data Set for Download or QSAR

Found 63 hits with Last Name = 'sarkar' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM15339 (6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...) Show SMILES Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of NNMT in human U2OS cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysis				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576030 (CHEMBL4860581) Show SMILES COc1cc2CCCCCc2cc1C(=O)Nc1ccc(cc1)C(C)(C)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455085 (CHEMBL4217817) Show SMILES COc1ccc(nn1)C(N)=O Show InChI InChI=1S/C6H7N3O2/c1-11-5-3-2-4(6(7)10)8-9-5/h2-3H,1H3,(H2,7,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455092 (CHEMBL4218043) Show SMILES COc1cc(C)c(cn1)C(N)=O Show InChI InChI=1S/C8H10N2O2/c1-5-3-7(12-2)10-4-6(5)8(9)11/h3-4H,1-2H3,(H2,9,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	588	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455087 (CHEMBL4207500) Show SMILES [2H]C([2H])([2H])Oc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	922	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Mus musculus)	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of NNMT in mouse 3T3L1 cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysis				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455095 (CHEMBL4206972) Show SMILES COc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576027 (CHEMBL4852930) Show SMILES COc1cc2CCCCCc2cc1C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576023 (CHEMBL4851250) Show SMILES COc1cc2CCCCCc2cc1NC(=O)c1ccc(cc1)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Mus musculus)	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of mouse NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576022 (CHEMBL1498496) Show SMILES COc1cc2CCCCc2cc1NC(=O)c1ccc(cc1)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92409 (Epoxyazadiradione) Show SMILES CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1 |c:12| Show InChI InChI=1S/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20-,21-,23-,25-,26+,27+,28-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology					Assay Description The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...				J Biol Chem 287: 24844-61 (2012) Article DOI: 10.1074/jbc.M112.341321 BindingDB Entry DOI: 10.7270/Q2RV0M83
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359714 (CHEMBL1927069) Show SMILES COc1cc(ccc1O)C1=NOC(COc2ccc(C=O)cc2)C1 |t:10| Show InChI InChI=1S/C18H17NO5/c1-22-18-8-13(4-7-17(18)21)16-9-15(24-19-16)11-23-14-5-2-12(10-20)3-6-14/h2-8,10,15,21H,9,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Plasmodium falciparum)	BDBM92409 (Epoxyazadiradione) Show SMILES CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1 |c:12| Show InChI InChI=1S/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20-,21-,23-,25-,26+,27+,28-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology					Assay Description The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...				J Biol Chem 287: 24844-61 (2012) Article DOI: 10.1074/jbc.M112.341321 BindingDB Entry DOI: 10.7270/Q2RV0M83
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor-like protein (Plasmodium yoelii)	BDBM92409 (Epoxyazadiradione) Show SMILES CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1 |c:12| Show InChI InChI=1S/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20-,21-,23-,25-,26+,27+,28-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology					Assay Description The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...				J Biol Chem 287: 24844-61 (2012) Article DOI: 10.1074/jbc.M112.341321 BindingDB Entry DOI: 10.7270/Q2RV0M83
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455086 (CHEMBL4204179) Show SMILES Cc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H8N2O/c1-5-2-3-6(4-9-5)7(8)10/h2-4H,1H3,(H2,8,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359718 (CHEMBL1927059) Show SMILES COc1cc(ccc1O)C1=NOC(CC(O)=O)C1 |t:10| Show InChI InChI=1S/C12H13NO5/c1-17-11-4-7(2-3-10(11)14)9-5-8(18-13-9)6-12(15)16/h2-4,8,14H,5-6H2,1H3,(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359713 (CHEMBL1927067) Show SMILES CCCCOC(=O)CC1CC(=NO1)c1ccc(OC)cc1 |c:10| Show InChI InChI=1S/C16H21NO4/c1-3-4-9-20-16(18)11-14-10-15(17-21-14)12-5-7-13(19-2)8-6-12/h5-8,14H,3-4,9-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359716 (CHEMBL1927057) Show SMILES OC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:6| Show InChI InChI=1S/C11H11NO4/c13-8-3-1-7(2-4-8)10-5-9(16-12-10)6-11(14)15/h1-4,9,13H,5-6H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359717 (CHEMBL1927058) Show SMILES COc1ccc(cc1)C1=NOC(CC(O)=O)C1 |t:9| Show InChI InChI=1S/C12H13NO4/c1-16-9-4-2-8(3-5-9)11-6-10(17-13-11)7-12(14)15/h2-5,10H,6-7H2,1H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92412 (Nimbin) Show SMILES COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@H](OC(C)=O)[C@H]2[C@@](C)(C=CC(=O)[C@]12C)C(=O)OC |c:32,t:14| Show InChI InChI=1S/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology					Assay Description The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...				J Biol Chem 287: 24844-61 (2012) Article DOI: 10.1074/jbc.M112.341321 BindingDB Entry DOI: 10.7270/Q2RV0M83
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359712 (CHEMBL1927066) Show SMILES COC(=O)CC1CC(=NO1)c1ccc(OC)cc1 |c:7| Show InChI InChI=1S/C13H15NO4/c1-16-10-5-3-9(4-6-10)12-7-11(18-14-12)8-13(15)17-2/h3-6,11H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of CYP2C9 (unknown origin)				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50455078 (CHEMBL4218848) Show SMILES CNc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H9N3O/c1-9-6-3-2-5(4-10-6)7(8)11/h2-4H,1H3,(H2,8,11)(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of CYP2C19 (unknown origin)				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor-like protein (Plasmodium yoelii)	BDBM92412 (Nimbin) Show SMILES COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@H](OC(C)=O)[C@H]2[C@@](C)(C=CC(=O)[C@]12C)C(=O)OC |c:32,t:14| Show InChI InChI=1S/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology					Assay Description The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...				J Biol Chem 287: 24844-61 (2012) Article DOI: 10.1074/jbc.M112.341321 BindingDB Entry DOI: 10.7270/Q2RV0M83
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Plasmodium falciparum)	BDBM92412 (Nimbin) Show SMILES COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@H](OC(C)=O)[C@H]2[C@@](C)(C=CC(=O)[C@]12C)C(=O)OC |c:32,t:14| Show InChI InChI=1S/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology					Assay Description The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...				J Biol Chem 287: 24844-61 (2012) Article DOI: 10.1074/jbc.M112.341321 BindingDB Entry DOI: 10.7270/Q2RV0M83
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576029 (CHEMBL4858433) Show SMILES COc1cc2CCCCCc2cc1C(=O)Nc1ccc(cc1)C(C)(C)O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50359719 (CHEMBL1927060) Show SMILES COC(=O)C1CC(=NO1)c1ccc(OC)c(OC)c1 |c:6| Show InChI InChI=1S/C13H15NO5/c1-16-10-5-4-8(6-11(10)17-2)9-7-12(19-14-9)13(15)18-3/h4-6,12H,7H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemical Biology Curated by ChEMBL					Assay Description Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...				Bioorg Med Chem 19: 7365-73 (2011) Article DOI: 10.1016/j.bmc.2011.10.056 BindingDB Entry DOI: 10.7270/Q2CR5TSR
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455093 (CHEBI:27410 | CHEMBL3542314) Show SMILES Cn1cc(ccc1=O)C(N)=O Show InChI InChI=1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455091 (CHEMBL4216237) Show SMILES CCc1ccc(cn1)C(N)=O Show InChI InChI=1S/C8H10N2O/c1-2-7-4-3-6(5-10-7)8(9)11/h3-5H,2H2,1H3,(H2,9,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455090 (CHEMBL4202617) Show SMILES COc1ccc(NC(C)=O)cn1 Show InChI InChI=1S/C8H10N2O2/c1-6(11)10-7-3-4-8(12-2)9-5-7/h3-5H,1-2H3,(H,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455089 (CHEMBL4209022) Show SMILES CCNC(=O)c1ccc(OC)nc1 Show InChI InChI=1S/C9H12N2O2/c1-3-10-9(12)7-4-5-8(13-2)11-6-7/h4-6H,3H2,1-2H3,(H,10,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455088 (CHEMBL4206735) Show SMILES COc1ccc(cn1)-c1nnn[nH]1 Show InChI InChI=1S/C7H7N5O/c1-13-6-3-2-5(4-8-6)7-9-11-12-10-7/h2-4H,1H3,(H,9,10,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50340090 (4-methoxybenzamide | CHEMBL449635) Show SMILES COc1ccc(cc1)C(N)=O Show InChI InChI=1S/C8H9NO2/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H2,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455084 (CHEMBL4214098) Show SMILES COc1ccc(C(N)=O)c(C)n1 Show InChI InChI=1S/C8H10N2O2/c1-5-6(8(9)11)3-4-7(10-5)12-2/h3-4H,1-2H3,(H2,9,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576032 (CHEMBL4869858) Show SMILES COc1cc2CCCCCc2cc1C(=O)Nc1ccc(cn1)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455082 (CHEMBL4215561) Show SMILES CCOc1nc(C)ccc1C(N)=O Show InChI InChI=1S/C9H12N2O2/c1-3-13-9-7(8(10)12)5-4-6(2)11-9/h4-5H,3H2,1-2H3,(H2,10,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455081 (CHEMBL4209724) Show SMILES CCOc1cc(C)ncc1C(N)=O Show InChI InChI=1S/C9H12N2O2/c1-3-13-8-4-6(2)11-5-7(8)9(10)12/h4-5H,3H2,1-2H3,(H2,10,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455080 (CHEMBL4207893) Show SMILES CSc1ccc(cn1)C(N)=O Show InChI InChI=1S/C7H8N2OS/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455079 (CHEMBL4210945) Show SMILES NC(=O)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C7H5F3N2O/c8-7(9,10)5-2-1-4(3-12-5)6(11)13/h1-3H,(H2,11,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM228815 (5-MeO-PZA) Show SMILES COc1cnc(cn1)C(N)=O Show InChI InChI=1S/C6H7N3O2/c1-11-5-3-8-4(2-9-5)6(7)10/h2-3H,1H3,(H2,7,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455077 (CHEMBL1997189) Show SMILES CN(C)c1ccc(cn1)C(N)=O Show InChI InChI=1S/C8H11N3O/c1-11(2)7-4-3-6(5-10-7)8(9)12/h3-5H,1-2H3,(H2,9,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455083 (CHEMBL4218838) Show SMILES COc1ccc(cc1F)C(N)=O Show InChI InChI=1S/C8H8FNO2/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4H,1H3,(H2,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...				Bioorg Med Chem Lett 28: 922-925 (2018) Article DOI: 10.1016/j.bmcl.2018.01.058 BindingDB Entry DOI: 10.7270/Q22Z184C
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576031 (CHEMBL4874245) Show SMILES COc1cc2CCCCCc2cc1C(=O)Nc1cc([nH]n1)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576028 (CHEMBL4849065) Show SMILES CC(C)(C)c1ccc(NC(=O)c2cc3CCCCCc3cc2O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50576026 (CHEMBL4876364) Show SMILES COc1cc2CCCCCc2nc1NC(=O)c1ccc(cn1)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02183 BindingDB Entry DOI: 10.7270/Q2W3814Z
					More data for this Ligand-Target Pair

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