Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM92409 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Tautomerase Activity Assay |
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IC50 | 9.5e+3± 1.7e+3 nM |
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Citation | Alam, A; Haldar, S; Thulasiram, HV; Kumar, R; Goyal, M; Iqbal, MS; Pal, C; Dey, S; Bindu, S; Sarkar, S; Pal, U; Maiti, NC; Bandyopadhyay, U Novel Anti-inflammatory Activity of Epoxyazadiradione against Macrophage Migration Inhibitory Factor: INHIBITION OF TAUTOMERASE AND PROINFLAMMATORY ACTIVITIES OF MACROPHAGE MIGRATION INHIBITORY FACTOR. J Biol Chem287:24844-61 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | Macrophage migration inhibitory factor (MIF) |
Type: | Enzyme |
Mol. Mass.: | 12844.38 |
Organism: | Plasmodium falciparum |
Description: | Q6Q3H7 |
Residue: | 116 |
Sequence: | MPCCEVITNVNLPDDNVQSTLSQIENAISDVMGKPLGYIMSNYDYQKNLRFGGSNEAYCF
VRITSIGGINRSNNSALADQITKLLVSNLNVKSRRIYVEFRDCSAQNFAFSGSLFG
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BDBM92409 |
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n/a |
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Name | BDBM92409 |
Synonyms: | Epoxyazadiradione |
Type | Small organic molecule |
Emp. Form. | C28H34O6 |
Mol. Mass. | 466.566 |
SMILES | CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1 |c:12| |
Structure |
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