| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-1 |
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| Ligand | BDBM50444909 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1761591 (CHEMBL4196838) |
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| IC50 | >100000±n/a nM |
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| Citation |  Tanaka, M; Zhu, Y; Shionyu, M; Ota, N; Shibata, N; Watanabe, C; Mizusawa, A; Sasaki, R; Mizukami, T; Shiina, I; Hasegawa, M Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death. Eur J Med Chem146:636-650 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-1 |
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| Name: | Proteasome subunit beta type-1 |
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| Synonyms: | PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26493.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1366691 |
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| Residue: | 241 |
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| Sequence: | MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEG
FSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAML
STILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQ
VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRK
D
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| BDBM50444909 |
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| n/a |
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| Name | BDBM50444909 |
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| Synonyms: | CHEMBL3099618 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H50N2O2 |
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| Mol. Mass. | 566.8158 |
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| SMILES | [#6]-[#6]\[#6](=[#6](/c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1)-c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1)-c1ccccc1 |
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| Structure | 
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