| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM50021956 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_41049 |
|---|
| IC50 | 260±n/a nM |
|---|
| Citation |  Micetich, RG; Maiti, SN; Spevak, P; Hall, TW; Yamabe, S; Ishida, N; Tanaka, M; Yamazaki, T; Nakai, A; Ogawa, K Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. J Med Chem30:1469-74 (1987) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | BLAC_STAAU | Beta-lactamase TEM | Penicillinase | blaZ |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 31367.53 |
|---|
| Organism: | Staphylococcus aureus |
|---|
| Description: | ChEMBL_41052 |
|---|
| Residue: | 281 |
|---|
| Sequence: | MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALDTKSGKEVKFNSDKRFA
YASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTY
SDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKT
LNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQAITYASRNDVAF
VYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
|
|
|
|---|
| BDBM50021956 |
|---|
| n/a |
|---|
| Name | BDBM50021956 |
|---|
| Synonyms: | CHEMBL285387 | Sodium; 3-methyl-2,2,6-trioxo-3-[1,2,3]triazol-1-ylmethyl-2lambda*6*-thia-bicyclo[3.2.0]heptane-4-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H12N3O5S |
|---|
| Mol. Mass. | 298.296 |
|---|
| SMILES | C[C@]1(Cn2ccnn2)[C@@H](C2C(CC2=O)S1(=O)=O)C([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
