| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50019670 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158835 |
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| IC50 | 1200±n/a nM |
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| Citation |  Tilley, JW; Burghardt, B; Burghardt, C; Mowles, TF; Leinweber, FJ; Klevans, L; Young, R; Hirkaler, G; Fahrenholtz, K; Zawoiski, S Pyrido[2,1-b]quinazolinecarboxamide derivatives as platelet activating factor antagonists. J Med Chem31:466-72 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50019670 |
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| n/a |
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| Name | BDBM50019670 |
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| Synonyms: | 2-Hydroxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (4-pyridin-3-yl-butyl)-amide | CHEMBL57480 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N4O3 |
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| Mol. Mass. | 388.4192 |
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| SMILES | Oc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 |
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| Structure | 
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