Compile Data Set for Download or QSAR

Found 34 hits with Last Name = 'fahrenholtz' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023323 (2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8...) Show SMILES Cc1cc2nc3ccc(cn3c(=O)c2cc1C)C(=O)NCCCCc1cncnc1 Show InChI InChI=1S/C23H23N5O2/c1-15-9-19-20(10-16(15)2)27-21-7-6-18(13-28(21)23(19)30)22(29)26-8-4-3-5-17-11-24-14-25-12-17/h6-7,9-14H,3-5,8H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50021516 (2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan...) Show SMILES COc1cc(cc(OC)c1OC)C1CC[C@@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023325 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCCCc1cncnc1 Show InChI InChI=1S/C26H29N5O2/c1-18(2)20-8-10-23-22(13-20)26(33)31-16-21(9-11-24(31)30-23)25(32)29-12-6-4-3-5-7-19-14-27-17-28-15-19/h8-11,13-18H,3-7,12H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019687 (CHEMBL1202755 | CHEMBL57825) Show SMILES CC(CCCc1cccnc1)NC(=O)c1ccc2nc3ccc(cc3c(=O)n2c1)C(C)C Show InChI InChI=1S/C26H28N4O2/c1-17(2)20-9-11-23-22(14-20)26(32)30-16-21(10-12-24(30)29-23)25(31)28-18(3)6-4-7-19-8-5-13-27-15-19/h5,8-18H,4,6-7H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019665 (2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8...) Show SMILES Cc1cc2nc3ccc(cn3c(=O)c2cc1C)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C24H24N4O2/c1-16-12-20-21(13-17(16)2)27-22-9-8-19(15-28(22)24(20)30)23(29)26-11-4-3-6-18-7-5-10-25-14-18/h5,7-10,12-15H,3-4,6,11H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019669 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C25H26N4O2/c1-17(2)19-8-10-22-21(14-19)25(31)29-16-20(9-11-23(29)28-22)24(30)27-13-4-3-6-18-7-5-12-26-15-18/h5,7-12,14-17H,3-4,6,13H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019678 (3-Methoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8-ca...) Show SMILES COc1ccc2c(c1)nc1ccc(cn1c2=O)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C23H22N4O3/c1-30-18-8-9-19-20(13-18)26-21-10-7-17(15-27(21)23(19)29)22(28)25-12-3-2-5-16-6-4-11-24-14-16/h4,6-11,13-15H,2-3,5,12H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019684 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCCCc1cccnc1 Show InChI InChI=1S/C27H30N4O2/c1-19(2)21-10-12-24-23(16-21)27(33)31-18-22(11-13-25(31)30-24)26(32)29-15-6-4-3-5-8-20-9-7-14-28-17-20/h7,9-14,16-19H,3-6,8,15H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023315 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES C[C@@H](CCCc1cccnc1)NC(=O)c1ccc2nc3ccc(cc3c(=O)n2c1)C(C)C Show InChI InChI=1S/C26H28N4O2/c1-17(2)20-9-11-23-22(14-20)26(32)30-16-21(10-12-24(30)29-23)25(31)28-18(3)6-4-7-19-8-5-13-27-15-19/h5,8-18H,4,6-7H2,1-3H3,(H,28,31)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019686 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cncnc1 Show InChI InChI=1S/C24H25N5O2/c1-16(2)18-6-8-21-20(11-18)24(31)29-14-19(7-9-22(29)28-21)23(30)27-10-4-3-5-17-12-25-15-26-13-17/h6-9,11-16H,3-5,10H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019676 (2-Methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-car...) Show SMILES Cc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C23H22N4O2/c1-16-7-9-20-19(13-16)23(29)27-15-18(8-10-21(27)26-20)22(28)25-12-3-2-5-17-6-4-11-24-14-17/h4,6-11,13-15H,2-3,5,12H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023324 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES C[C@H](CCCc1cccnc1)NC(=O)c1ccc2nc3ccc(cc3c(=O)n2c1)C(C)C Show InChI InChI=1S/C26H28N4O2/c1-17(2)20-9-11-23-22(14-20)26(32)30-16-21(10-12-24(30)29-23)25(31)28-18(3)6-4-7-19-8-5-13-27-15-19/h5,8-18H,4,6-7H2,1-3H3,(H,28,31)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019671 (2-Isopropoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8...) Show SMILES CC(C)Oc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C25H26N4O3/c1-17(2)32-20-9-10-22-21(14-20)25(31)29-16-19(8-11-23(29)28-22)24(30)27-13-4-3-6-18-7-5-12-26-15-18/h5,7-12,14-17H,3-4,6,13H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50006048 (2-methoxy-3-(octadecylcarbamoyloxy)propyl 2-(thiaz...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP([O-])(=O)OCC[n+]1ccsc1)OC Show InChI InChI=1S/C28H53N2O7PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-29-28(31)35-24-27(34-2)25-37-38(32,33)36-22-20-30-21-23-39-26-30/h21,23,26-27H,3-20,22,24-25H2,1-2H3,(H-,29,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019688 (2-Bromo-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carb...) Show SMILES Brc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C22H19BrN4O2/c23-17-7-8-19-18(12-17)22(29)27-14-16(6-9-20(27)26-19)21(28)25-11-2-1-4-15-5-3-10-24-13-15/h3,5-10,12-14H,1-2,4,11H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019680 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCCc1cccnc1 Show InChI InChI=1S/C26H28N4O2/c1-18(2)20-9-11-23-22(15-20)26(32)30-17-21(10-12-24(30)29-23)25(31)28-14-5-3-4-7-19-8-6-13-27-16-19/h6,8-13,15-18H,3-5,7,14H2,1-2H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019675 (2-Methoxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8-ca...) Show SMILES COc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C23H22N4O3/c1-30-18-8-9-20-19(13-18)23(29)27-15-17(7-10-21(27)26-20)22(28)25-12-3-2-5-16-6-4-11-24-14-16/h4,6-11,13-15H,2-3,5,12H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023321 (5-{4-[(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinaz...) Show SMILES Cc1cc2nc3ccc(cn3c(=O)c2cc1C)C(=O)NCCCCc1cnc[n+](C)c1 Show InChI InChI=1S/C24H25N5O2/c1-16-10-20-21(11-17(16)2)27-22-8-7-19(14-29(22)24(20)31)23(30)26-9-5-4-6-18-12-25-15-28(3)13-18/h7-8,10-15H,4-6,9H2,1-3H3/p+1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019673 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCCCCc1cccnc1 Show InChI InChI=1S/C28H32N4O2/c1-20(2)22-11-13-25-24(17-22)28(34)32-19-23(12-14-26(32)31-25)27(33)30-16-7-5-3-4-6-9-21-10-8-15-29-18-21/h8,10-15,17-20H,3-7,9,16H2,1-2H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023322 (1-{6-[(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinaz...) Show SMILES Cc1cc2nc3ccc(cn3c(=O)c2cc1C)C(=O)NCCCCCC[n+]1ccccc1 Show InChI InChI=1S/C26H28N4O2/c1-19-16-22-23(17-20(19)2)28-24-11-10-21(18-30(24)26(22)32)25(31)27-12-6-3-4-7-13-29-14-8-5-9-15-29/h5,8-11,14-18H,3-4,6-7,12-13H2,1-2H3/p+1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023319 (2-Isopropyl-8-(6-pyridin-3-yl-hexyl)-pyrido[2,1-b]...) Show SMILES CC(C)c1ccc2nc3ccc(CCCCCCc4cccnc4)cn3c(=O)c2c1 Show InChI InChI=1S/C26H29N3O/c1-19(2)22-12-13-24-23(16-22)26(30)29-18-21(11-14-25(29)28-24)9-6-4-3-5-8-20-10-7-15-27-17-20/h7,10-19H,3-6,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019672 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCc1cccnc1 Show InChI InChI=1S/C24H24N4O2/c1-16(2)18-7-9-21-20(13-18)24(30)28-15-19(8-10-22(28)27-21)23(29)26-12-4-6-17-5-3-11-25-14-17/h3,5,7-11,13-16H,4,6,12H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023320 (3-{4-[(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinaz...) Show SMILES Cc1cc2nc3ccc(cn3c(=O)c2cc1C)C(=O)NCCCCc1ccc[n+](C)c1 Show InChI InChI=1S/C25H26N4O2/c1-17-13-21-22(14-18(17)2)27-23-10-9-20(16-29(23)25(21)31)24(30)26-11-5-4-7-19-8-6-12-28(3)15-19/h6,8-10,12-16H,4-5,7,11H2,1-3H3/p+1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023318 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)S(=O)(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C24H26N4O3S/c1-17(2)19-8-10-22-21(14-19)24(29)28-16-20(9-11-23(28)27-22)32(30,31)26-13-4-3-6-18-7-5-12-25-15-18/h5,7-12,14-17,26H,3-4,6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023316 (2-Isopropyl-8-[(4-pyridin-3-yl-butylamino)-methyl]...) Show SMILES CC(C)c1ccc2nc3ccc(CNCCCCc4cccnc4)cn3c(=O)c2c1 Show InChI InChI=1S/C25H28N4O/c1-18(2)21-9-10-23-22(14-21)25(30)29-17-20(8-11-24(29)28-23)16-26-12-4-3-6-19-7-5-13-27-15-19/h5,7-11,13-15,17-18,26H,3-4,6,12,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50023317 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)OCCCCc1cccnc1 Show InChI InChI=1S/C25H25N3O3/c1-17(2)19-8-10-22-21(14-19)24(29)28-16-20(9-11-23(28)27-22)25(30)31-13-4-3-6-18-7-5-12-26-15-18/h5,7-12,14-17H,3-4,6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019689 (3-Chloro-11-oxo-11H-pyrido[2,1-b]quinazoline-8-car...) Show SMILES Clc1ccc2c(c1)nc1ccc(cn1c2=O)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C22H19ClN4O2/c23-17-7-8-18-19(12-17)26-20-9-6-16(14-27(20)22(18)29)21(28)25-11-2-1-4-15-5-3-10-24-13-15/h3,5-10,12-14H,1-2,4,11H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019670 (2-Hydroxy-11-oxo-11H-pyrido[2,1-b]quinazoline-8-ca...) Show SMILES Oc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cccnc1 Show InChI InChI=1S/C22H20N4O3/c27-17-7-8-19-18(12-17)22(29)26-14-16(6-9-20(26)25-19)21(28)24-11-2-1-4-15-5-3-10-23-13-15/h3,5-10,12-14,27H,1-2,4,11H2,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019677 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NC(C)(C)CCCc1cccnc1 Show InChI InChI=1S/C27H30N4O2/c1-18(2)20-9-11-23-22(15-20)26(33)31-17-21(10-12-24(31)29-23)25(32)30-27(3,4)13-5-7-19-8-6-14-28-16-19/h6,8-12,14-18H,5,7,13H2,1-4H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019668 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1ccncc1 Show InChI InChI=1S/C25H26N4O2/c1-17(2)19-6-8-22-21(15-19)25(31)29-16-20(7-9-23(29)28-22)24(30)27-12-4-3-5-18-10-13-26-14-11-18/h6-11,13-17H,3-5,12H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019683 (11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic a...) Show SMILES O=C(NCCCCc1cccnc1)c1ccc2nc3ccccc3c(=O)n2c1 Show InChI InChI=1S/C22H20N4O2/c27-21(24-13-4-3-6-16-7-5-12-23-14-16)17-10-11-20-25-19-9-2-1-8-18(19)22(28)26(20)15-17/h1-2,5,7-12,14-15H,3-4,6,13H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019690 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCc1cccnc1 Show InChI InChI=1S/C23H22N4O2/c1-15(2)17-5-7-20-19(12-17)23(29)27-14-18(6-8-21(27)26-20)22(28)25-11-9-16-4-3-10-24-13-16/h3-8,10,12-15H,9,11H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019681 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCn1ccnc1 Show InChI InChI=1S/C23H25N5O2/c1-16(2)17-5-7-20-19(13-17)23(30)28-14-18(6-8-21(28)26-20)22(29)25-9-3-4-11-27-12-10-24-15-27/h5-8,10,12-16H,3-4,9,11H2,1-2H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50019679 (2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1ccccn1 Show InChI InChI=1S/C25H26N4O2/c1-17(2)18-9-11-22-21(15-18)25(31)29-16-19(10-12-23(29)28-22)24(30)27-14-6-4-8-20-7-3-5-13-26-20/h3,5,7,9-13,15-17H,4,6,8,14H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand				J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6
					More data for this Ligand-Target Pair