Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-activating factor receptor (Homo sapiens (Human)) | BDBM50021516 (2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. Curated by ChEMBL | Assay Description Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]-PAF as radioligand | J Med Chem 31: 466-72 (1988) BindingDB Entry DOI: 10.7270/Q2KK99S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor receptor (Cavia porcellus) | BDBM50021516 (2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of PAF receptor binding to rabbit platelet plasma membranes | J Med Chem 29: 1917-21 (1986) BindingDB Entry DOI: 10.7270/Q2X63KZS | |||||||||||
More data for this Ligand-Target Pair |