| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Ligand | BDBM9460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_53751 |
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| IC50 | 30000±n/a nM |
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| Citation |  Leung, CS; Rowlands, MG; Jarman, M; Foster, AB; Griggs, LJ; Wilman, DE Analogues of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents. J Med Chem30:1550-4 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Synonyms: | CP11A_BOVIN | CYP11A1 | CYPXIA1 | Cholesterol desmolase | Cholesterol side-chain cleavage enzyme, mitochondrial | Cytochrome P450 11A1 | Cytochrome P450 11A1 (CYP11A1) | P450(scc) |
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| Type: | Protein |
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| Mol. Mass.: | 60346.75 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | P00189 |
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| Residue: | 520 |
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| Sequence: | MLARGLPLRSALVKACPPILSTVGEGWGHHRVGTGEGAGISTKTPRPYSEIPSPGDNGWL
NLYHFWREKGSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPER
YDIPPWLAYHRYYQKPIGVLFKKSGTWKKDRVVLNTEVMAPEAIKNFIPLLNPVSQDFVS
LLHKRIKQQGSGKFVGDIKEDLFHFAFESITNVMFGERLGMLEETVNPEAQKFIDAVYKM
FHTSVPLLNVPPELYRLFRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRRKTEFRNYPGI
LYCLLKSEKMLLEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARR
QAEGDISKMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQDYLIPAKTLVQVAIYA
MGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE
NFKVEMQHIGDVDTIFNLILTPDKPIFLVFRPFNQDPPQA
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| BDBM9460 |
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| n/a |
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| Name | BDBM9460 |
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| Synonyms: | 3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione | Aminoglutethimide AG, 4 | CHEMBL488 | Cytadren | EN300-53368 | Elipten | aminoglutethimide (AG) |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2O2 |
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| Mol. Mass. | 232.2783 |
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| SMILES | CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 |
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| Structure | 
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