| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50059964 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_211334 (CHEMBL820777) |
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| IC50 | 550±n/a nM |
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| Citation |  Chen, K; Kuo, SC; Hsieh, MC; Mauger, A; Lin, CM; Hamel, E; Lee, KH Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization. J Med Chem40:3049-56 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
|
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|
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| BDBM50059964 |
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| n/a |
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| Name | BDBM50059964 |
|---|
| Synonyms: | 6-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-one | 6-methyl-2-(naphthalen-1-yl)-1,8-naphthyridin-4(1H)-one | CHEMBL50666 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C19H14N2O |
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| Mol. Mass. | 286.3273 |
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| SMILES | Cc1cnc2nc(cc(O)c2c1)-c1cccc2ccccc12 |
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| Structure | 
|
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